Francois, Pognan: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity

John O'Brien, Ian Wilson, Terry Orton, François Pognan

Journal:

Year:

2000

Language:

english

File:

PDF, 651 KB

english, 2000

2

Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology

Robert Tonge, Joanne Shaw, Brian Middleton, Rachel Rowlinson, Steve Rayner, Janice Young, Francois Pognan, Edward Hawkins, Ian Currie, Matthew Davison

Journal:

Year:

2001

Language:

english

File:

PDF, 4.37 MB

english, 2001

3

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

Muireann Coen, Stefan U. Ruepp, John C. Lindon, Jeremy K. Nicholson, François Pognan, Eva M. Lenz, Ian D. Wilson

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2004

Language:

english

File:

PDF, 532 KB

english, 2004

4

Imatinib does not induce cardiotoxicity at clinically relevant concentrations in preclinical studies

Armin Wolf, Philippe Couttet, Min Dong, Olivier Grenet, Marcia Heron, Ursula Junker, Ulrich Laengle, David Ledieu, Estelle Marrer, Anja Nussher, Elke Persohn, Francois Pognan, Gilles-Jacques Rivière,

Journal:

Leukemia Research

Year:

2010

Language:

english

File:

PDF, 452 KB

english, 2010

5

Preclinical evaluation of potential nilotinib cardiotoxicity

Armin Wolf, Philippe Couttet, Min Dong, Olivier Grenet, Marcia Heron, Ursula Junker, David Ledieu, Andreas Mahl, Estelle Marrer, Elke Persohn, Francois Pognan, Wei Zhou, Jeffrey Tsao, Danielle Roman

Journal:

Leukemia Research

Year:

2011

Language:

english

File:

PDF, 333 KB

english, 2011

6

A novel method for quantification of canalicular transporter inhibition in primary rat hepatocyte sandwich cultures

Jane Hopwood, Claire Summers, François Pognan, Gillian Barrett, Kevin Jones, Romuald Laine, Gerry Kenna

Journal:

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

7

Development of a Novel LC-MS/MS Method to Quantify F2-Isoprostanes in Biological Samples

Min Dong, Falk Rohrbach, Marianne Schwald, Odile Weber, Virginie Riebel, Francois Pognan, Armin Wolf

Journal:

Free Radical Biology and Medicine

Year:

2010

Language:

english

File:

PDF, 184 KB

english, 2010

8

A carboline derivative as a novel mammalian DNA topoisomerase II targeting agent

François Pognan, Jean-Marie Saucier, Claude Paoletti, Lukasz Kaczmarek, Pawel Nantka-Namirski, Marian Mordarski, Wanda Peczynska-Czoch

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 990 KB

english, 1992

9

In silico prediction of in vivo toxicities (eTox)—The Innovative Medicines Initiative Approach

Thomas Steger-Hartmann, Francois Pognan, Ferran Sanz, Carlos Acedo Diaz

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 83 KB

english, 2009

10

Genome-wide analysis of DNA methylation profiles in a preclinical animal model of non-genotoxic carcinogenesis

Jonathan Moggs, Soon Siong Teo, Arne Mueller, Laurent Morawiec, Tim Roloff, David Heard, Frank Staedtler, Dirk Schubeler, Fabian Mohn, Jay Goodman, Jennifer Phillips, Natasa Zamurovic, Francois Pognan

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 61 KB

english, 2009

11

Synthesis and Structure-Activity Relationship of Methyl-Substituted Indolo[2,3-b]quinolines: Novel Cytotoxic, DNA Topoisomerase II Inhibitors

Peczynska-Czoch, Wanda, Pognan, Francois, Kaczmarek, Lukasz, Boratynski, Janusz

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.45 MB

english, 1994

12

Protein kinase C inhibition induced steroid hormonal perturbation in rat in vivo

Heiko, Schadt, Zuhal, Dincer, Marianne, Schwald, Audrey, Dietz, David, Ledieu, Andre, Cordier, Maria, Papoutsi, Ursula, Junker Walker, Fiona, Spence, Salah-Dine, Chibout, Armin, Wolf, Francois, Pognan

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 77 KB

english, 2013

13

ABSTRACT OF The FitzPatrick Lectures FOR 1904.

Heiko, Schadt, Zuhal, Dincer, Marianne, Schwald, Audrey, Dietz, David, Ledieu, Andre, Cordier, Maria, Papoutsi, Ursula, Junker Walker, Fiona, Spence, Salah-Dine, Chibout, Armin, Wolf, Francois, Pognan

Journal:

Year:

1904

Language:

english

File:

PDF, 845 KB

english, 1904

14

Determination of liver specific toxicities in rat hepatocytes by High Content Imaging during 2-week multiple treatment

Germano, Davide, Uteng, Marianne, Couttet, Philippe, Grenet, Olivier, Chibout, Salah-Dine, Pognan, Francois, Wolf, Armin

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 96 KB

english, 2013

15

α-Anomeric DNA: β-RNA hybrids as new synthetic inhibitors of Escherichia coli RNase H, Drosophila embryo RNase H and M-MLV reverse transcriptase

Bloch, Evelyne, Lavignon, Marc, Bertrand, Jean-Rémi, Pognan, François, Morvan, François, Malvy, Claude, Rayner, Bernard, Imbach, Jean-Louis, Paoletti, Claude

Journal:

Year:

1988

Language:

english

File:

PDF, 1.23 MB

english, 1988

16

An Integrated Metabonomic Investigation of Acetaminophen Toxicity in the Mouse Using NMR Spectroscopy

Coen, Muireann, Lenz, Eva M., Nicholson, Jeremy K., Wilson, Ian D., Pognan, Francois, Lindon, John C.

Journal:

Chemical Research in Toxicology

Year:

2003

Language:

english

File:

PDF, 179 KB

english, 2003

17

Bile acids profiling of rat plasma after treatment with Cyclosporin A

Schadt, Heiko, Stiehl, Daniel, Schwald, Marianne, Vieira, Catia Vicente, Dietz, Audrey, Penno, Carlos, Chibout, Salah-Dine, Moulin, Pierre, Pognan, Francois, Wolf, Armin

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 73 KB

english, 2014

18

Investigative safety science as a competitive advantage for Pharma

Moggs, Jonathan, Moulin, Pierre, Pognan, Francois, Brees, Dominique, Leonard, Michele, Busch, Steve, Cordier, Andre, Heard, David J, Kammüller, Michael, Merz, Michael, Bouchard, Page, Chibout, Salah-D

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Year:

2012

Language:

english

File:

PDF, 313 KB

english, 2012

19

Ensuring confidence in predictions: A scheme to assess the scientific validity of in silico models

Hewitt, Mark, Ellison, Claire M., Cronin, Mark T.D., Pastor, Manuel, Steger-Hartmann, Thomas, Munoz-Muriendas, Jordi, Pognan, Francois, Madden, Judith C.

Journal:

Advanced Drug Delivery Reviews

Year:

2015

Language:

english

File:

PDF, 1.60 MB

english, 2015

20

Genomics, proteomics and metabonomics in toxicology: hopefully not ‘fashionomics’

Pognan, Francois

Journal:

Pharmacogenomics

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

21

Inroads to Predict in Vivo Toxicology—An Introduction to the eTOX Project

Briggs, Katharine, Cases, Montserrat, Heard, David J., Pastor, Manuel, Pognan, François, Sanz, Ferran, Schwab, Christof H., Steger-Hartmann, Thomas, Sutter, Andreas, Watson, David K., Wichard, Jörg D.

Journal:

International Journal of Molecular Sciences

Year:

2012

Language:

english

File:

PDF, 1.11 MB

english, 2012

22

Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment

Germano, Davide, Uteng, Marianne, Pognan, Francois, Chibout, Salah-Dine, Wolf, Armin

Journal:

Toxicology in Vitro

Year:

2014

Language:

english

File:

PDF, 5.28 MB

english, 2014

23

The eTOX Data-Sharing Project to Advance in Silico Drug-Induced Toxicity Prediction

Cases, Montserrat, Briggs, Katharine, Steger-Hartmann, Thomas, Pognan, François, Marc, Philippe, Kleinöder, Thomas, Schwab, Christof, Pastor, Manuel, Wichard, Jörg, Sanz, Ferran

Journal:

International Journal of Molecular Sciences

Year:

2014

Language:

english

File:

PDF, 4.61 MB

english, 2014

24

Bile acids in drug induced liver injury: Key players and surrogate markers

Schadt, Heiko S., Wolf, Armin, Pognan, Francois, Chibout, Salah-Dine, Merz, Michael, Kullak-Ublick, Gerd A.

Journal:

Clinics and Research in Hepatology and Gastroenterology

Year:

2016

Language:

english

File:

PDF, 1.76 MB

english, 2016

25

Comparative renal safety assessment of the hepatitis B drugs, adefovir, tenofovir, telbivudine and entecavir in rats

Uteng, Marianne, Mahl, Andreas, Beckmann, Nicolau, Piaia, Alessandro, Ledieu, David, Dubost, Valerie, Tritto, Elaine, Wolf, Armin, Moulin, Pierre, Li, Li, Chibout, Salah-Dine, Pognan, Francois

Journal:

Toxicological Sciences

Year:

2016

Language:

english

File:

PDF, 2.40 MB

english, 2016

26

OntoBrowser: a collaborative tool for curation of ontologies by subject matter experts

Ravagli, Carlo, Pognan, Francois, Marc, Philippe

Journal:

Year:

2016

Language:

english

File:

PDF, 132 KB

english, 2016

27

Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin

Brecht, Karin, Riebel, Virginie, Couttet, Philippe, Paech, Franziska, Wolf, Armin, Chibout, Salah-Dine, Pognan, Francois, Krähenbühl, Stephan, Uteng, Marianne

Journal:

Toxicology in Vitro

Year:

2017

Language:

english

File:

PDF, 2.33 MB

english, 2017

28

Legacy data sharing to improve drug safety assessment: the eTOX project

Sanz, Ferran, Pognan, François, Steger-Hartmann, Thomas, Díaz, Carlos, Cases, Montserrat, Pastor, Manuel, Marc, Philippe, Wichard, Joerg, Briggs, Katharine, Watson, David K., Kleinöder, Thomas, Yang,

Journal:

Nature Reviews Drug Discovery

Year:

2017

Language:

english

File:

PDF, 118 KB

english, 2017

29

Preclinical ontologies – A key feature for toxicity data exchange and mining

Drew, Philip, Pognan, Francois, Marc, Philippe, Ravagli, Carlo

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 84 KB

english, 2017

30

Improving the Safety Assessment of Chemicals and Drug Candidates by the Integration of Bio-informatics and Chemoinformatics Data

Steger-Hartmann, Thomas, Pognan, Francois

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2018

Language:

english

File:

PDF, 1.46 MB

english, 2018

31

Learning from approved kinase inhibitors to better inform on the safety risks of specific kinases

Vicart, Axel, Kinyamu-Akunda, Jacqueline, Whitebread, Steven, Dumotier, Berengere, Urban, Laszlo, Kluwe, William, Moggs, Jonathan, Pognan, François, Chibout, Salah-Dine

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 54 KB

english, 2017

32

The IMI eTOX initiative – Data mining, read-across and predictive models for target evaluation and early drug candidate assessment

Steger-Hartmann, Thomas, Pognan, Francois, Sanz, Ferran

Journal:

Toxicology Letters

Year:

2017

Language:

english

File:

PDF, 84 KB

english, 2017

33

Induction of hemangiosarcoma in mice after chronic treatment with S1P-modulator siponimod and its lack of relevance to rat and human

Pognan, Francois, Mahl, J. Andreas, Papoutsi, Maria, Ledieu, David, Raccuglia, Marc, Theil, Diethilde, Voytek, Sarah B., Devine, Patrick J., Kubek-Luck, Katie, Claudio, Natalie, Cordier, Andre, Heier,

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

34

Key Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation Plans

Atienzar, Franck A., Blomme, Eric A., Chen, Minjun, Hewitt, Philip, Kenna, J. Gerry, Labbe, Gilles, Moulin, Frederic, Pognan, Francois, Roth, Adrian B., Suter-Dick, Laura, Ukairo, Okechukwu, Weaver, R

Journal:

BioMed Research International

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

35

CSF-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes

Pognan, Francois, Couttet, Philippe, Demin, Ivan, Jaitner, Birgit, Pang, Yinuo, Roubenoff, Ronenn, Sutter, Esther, Timsit, Yoav, Valentin, Marie Anne, Vogel, Beate, Woerly, Gaetane, Wolf, Armin, Schra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

File:

PDF, 2.13 MB

2019

36

CSF-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes

Pognan, Francois, Couttet, Philippe, Demin, Ivan, Jaitner, Birgit, Pang, Yinuo, Roubenoff, Ronenn, Sutter, Esther, Timsit, Yoav, Valentin, Marie Anne, Vogel, Beate, Woerly, Gaetane, Wolf, Armin, Schra

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2019

Language:

english

File:

PDF, 2.13 MB

english, 2019

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@z-lib.do

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски